VIKAS KAUSHIK, PREETI SHARMA, ADITI ARYA, ANIL SINDHU* AND AJAY SINGH
Department of Biotechnology, DCR University of Science & Technology, Murthal, Sonepat-131 039 (Haryana),
India
*(e-mail : sindhu.biotech@gmail.com; Mobile : 9468349982)
(Received : January 5, 2019; Accepted : March 20, 2019)
ABSTRACT
Ophiocordyceps sinensis is known for its extensive therapeutic potential (antioxidant, antiaging, antitumor
and antimicrobial activity) and nutraceutical properties. Soups are consumed for nutritive benefits and also
useful for patients whose intake of bulk food is restricted due to several pathological reasons imposed by
diseases. Dehydrated soup mix is preferred because of its less volume and long shelf life at optimum
temperature. In the present study, soup mix was formulated with 2 to 10% O. sinensis powder. Significant
improvement in the phenol content, flavonoid content and free radical scavenging activity contributed to the
total reducing power and antioxidant potential of this soup mix. Total phenol content increased up to 2.77
mg/g of gallic acid from 0.95 mg/g, flavonoid content increased up to 4.38 mg/g quercetin in soup fortified
with 10% O. sinensis powder. Concentration dependent scavenging activity was evaluated using DPPH and
NO assays. IC50 (scavenging of 50% 1, 1-diphenyl-2-picrylhydrazyl and nitric oxide radicals) values reduced
from 208.92 to 37.93 μg/ml and 389.04 to 43.65 μg/ml, respectively, for DPPH and NO assays.
Key words :Antioxidant potential, flavonoid content, free radical scavenging activity, nutraceutical,Ophiocordyceps sinensis