P. SAMPATHKUMAR, S. BHUVANESWARI*, R. SIVAKUMAR AND R. MADHUMITHA
Department of Chemistry and Biosciences, SASTRA Deemed to be University, Srinivasa Ramanujan Centre,
Kumbakonam-612 001(Tamil Nadu), India
*(e-mail: bhuvaneswari@src.sastra.edu; Mobile: 9047012358)
(Received: July 10, 2022; Accepted: November 14, 2022)
ABSTRACT
Globally, brushite and struvite kidney stones are one of the aged known diseases in both men and
women causing critical urinary disarray. So, the present study accomplished the effect of aqueous
extracts of Linum usitatissimum preventing stone. In vitro study brushite and struvite stones were gel
formed and treated with extracts of L. usitatissimum at different concentrations. The crystal formation
was analyzed by the FTIR and XRD method. The maximum inhibition of crystals using L. usitatissimum
extracts ranged from 1.68 to 0.30 g for brushite crystal and 1.74 to 0.12 g for struvite crystal. Additionally, the better inhibition of bacterial and fungal activity was observed at the concentration ranging from 60-100 µg/ml. In conclusion, good antibacterial, antifungal and antiurolithiatic activity was recorded for L. usitatissimum extract.
Key words : Calcium chloride, struvite crystals, magnesium acetate, anticrystal, antibacterial