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Histological Changes in the Placenta and Some Physiological Effects for Aborted Women Infected with Toxoplasma gondii


Biology Department, Faculty of Education for Girls, Kufa University, Iraq
*(e-mail :; Mobile : 00964-7814544585)
(Received : July 11, 2019; Accepted : September 14, 2019)


The study included physiological and histological examinations of 70 women who were infected with the disease of cats. The samples were divided into two groups : the first 10 did not control the control group
and the second 60 were women who underwent abortions. The blood samples were taken and physiological tests were carried out for both groups and samples were taken from 25 placenta. The second group was subjected to the preparation of sections and study of textiles. The results of the study showed a significant increase in levels of mononaldehyde and a decrease in the level of nitric oxide and clotathione in the infected group compared to the control group. There was also a significant increase in the levels of ALP, ALT, AST in the infected group compared with the control group. Histological changes that occurred in the
tissue sections of the placenta of aborted women showed a collapse of the placenta tissue because of the rapid reproduction of the parasite and the presence of large spaces in the tissue due to the formation of tissue bags of the parasite causing the death of cells forming the placenta tissue because of secretions and toxins produced by the parasite resulting in abortion or congenital malformations in the fetus and neonatal nervous system injuries.
Key words : Histological changes, placenta, physiological effects, abortion, Toxoplasma gondii