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Immunological Study of Growth Differentiation Factor 15 (GDF 15) in Relation to Aborted Women

SAJAD ALWAN KITAB AND ADHRAA BAQIR HASSAN
University of Kufa, Faculty of Science, Department of Biology, Najaf, Iraq
*(e-mail : adhraa.alshabawy@uokufa.edu.iq; Mobile : (00964)+7801103720) (Received : May 19, 2019; Accepted : July 12, 2019)

ABSTRACT

This study was conducted on randomly selected 60 aborted women suffering from miscarriage in Al-Zahraa Teaching Hospital in Al-Najaf province, Iraq and a group of 28 apparently control groups (14 pregnancy and 14 non-pregnancy). The study was carried out from September 2018 to February 2019. The age of patients and control groups ranged from 20 to 39 years, weight <65 to >76 kg and gestational age first trimester, second trimester. The results demonstrated that there was a significant increase (P0. 05) in weight in aborted women and pregnancy group in comparison with the non-pregnancy group. There was significant decrease (P0. 05) in GDF 15 level of aborted women in comparison with pregnancy group, whereas there was increase (P0. 05) in GDF 15 level in pregnancy group as compared with non-pregnancy group. Significant increase was in weight group of aborted women (>76 kg, 66-75 kg) as compared with (<65 kg). Similarly, there was significant increase (P0. 05) in GDF 15 level of weight groups (>76 kg) as compared with weight groups (<65 kg, 66-75 kg), whereas low significant increase (P0. 05) in age (30-39) in comparison with age (20-29) and significant increase (P0.05) in GDF level in age (30-39) in comparison with age (20-29). Significant positive correlation (P0.05) was observed between weight (kg) and GDF 15 level of miscarried women and between gestational age (week) and GDF 15 level of aborted women. Key words : Miscarriage, aborted women, pregnancy, Al-Najaf province