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Risk Assessment of Cadmium and Lead in Herbal Decoction of Tinospora cordifolia Leaves and their Antibacterial Activity on Pathogenic Gram-negative Bacteria

JYOTI JAGLAN*, SAVITA JAGLAN, ANDREW C. SINGER AND PRAVEEN SHARMA
Department of Environmental Science and Engineering, Guru Jambheshwar University of Science and Technology,
Hisar-125 001 (Haryana), India
*(e-mail : rs160481003@gjust.org; Mobile : 98127 22512)
(Received : April 5, 2022; Accepted : May 5, 2022)

ABSTRACT

Tinospora cordifolia possesses antimicrobial, anti-inflammatory, vaso-relaxing activity and
phytoremediation properties. The present study focused on the toxicological risk assessment of herbal
decoction. Two prominent heavy metals viz., cadmium and lead were analyzed using inductively coupled
plasma- optical emission spectroscopy (ICP-OES). A comparative study between hot-plate microwave
digestion of the sample was also performed. The outcomes of the study showed a higher amount of
targeted metals but a little lesser than the permissible limit of WHO. Further the efficiency of decoction
gram-negative pathogenic bacteria strain with multiple drug resistance (MDR) was checked by estimating
its antibacterial activity. The results of the study provided its authenticity as herbal remedy with effective
antibacterial properties. Further in situ hazard assessment of heavy metals in T. cordifolia cell lines on
various micro-organisms is required.
Key words : Tinospora cordifolia, decoction, inductively coupled plasma-optical emission spectroscopy, multiple drug-resistan