Search for content, post, videos

Serum T.Ca, PO4=, Mg+2, Na+ and K+ in T2DM Patient

ZAINAB HUSSEIN ALHILLAWI, MUNTADHER MOHAMMAD ALI AND MAHA ABDULSAHIB MUHAMMAD
Department of Chemistry, College of Science, University of Kufa, Iraq
*(e-mail : zainab.alhillawi@uokufa.edu.iq; Mobile : (0964) 07810135111)
(Received : September 7, 2021; Accepted : November 11, 2021)

ABSTRACT

In Iraq, the prevalence of type 2 diabetes mellitus (T2DM) ranged about 1.4 million which is nearly 8.5%.
The patients with diabetes are commonly caused by electrolyte disorders such as calcium ion (Ca+2),
phosphate (PO4=), magnesium (Mg+2), sodium (Na+) and potassium (K+). Sixty-five patients participated in this study. Their ages ranged between 45-60 years and the mean of BMI to patients 23.55±4.56. The mean of random blood glucose (RBG) and HbA1c was 288.42±68.63 mg/dl, 9.08±1.9%, respectively. In contrast, apparently 30 people were selected as a control group. Their age range was comparable to that of patients and the mean of BMI equal 22.94±3.15. The mean of RBG and HbA1c was 101.9±11.18 mg/dl and 5.03±0.63%, respectively. Five electrolytes were measured [serum total calcium (T.Ca), PO4=, Mg+2, Na+ and K+] by spectrophotometer methods. There was a significant increase in serum T.Ca, PO4= and K+ in diabetes patients, while no significant difference in Mg+2 and Na+ with healthy group. Increased serum T.Ca formed Ca+2– channels disorder or kidney diseases and metabolic disorders caused defect in serum T.Ca and PO4=. The insulin deficiency and healthy diet increased serum K+, finally uncontrolled blood glucose affecting many tissues and organs that affect electrolytes level.
Key words : : Hyperkalemia, calcium, sodium, diabetes mellitus