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Comparative Antimicrobial Activity and Antioxidant Profiling of Euphorbia hirta, Euphorbia milli and Euphorbia pulcherrima

Shweta Sundriyal, Shrishti, Pallavi Dheer, Priya Thapliyal, Ayushi Arora, Aditi Sharma, Vimlendu Bhushan Sinha, Manish Dev Sharma and Indra Rautela
Department of Biotechnology, School of Basic and Applied Sciences, Shri Guru Ram Rai University, Patel Nagar, Dehradun-248 001 (Uttarakhand), India
*(e-mail :; Mobile : 8430633253)
(Received : May 29, 2020; Accepted : July 25, 2020)


Euphorbia hirta, Euphorbia milli and Euphorbia pulcherrima belong to the Euphorbia genus which is popular for its medicinal attributes in the folklore and cultural traditions countries in India, China, Pakistan and Brazil, etc. These plants were targeted for studying their antioxidant potential and carried out comparative analysis amongst these species. The full antioxidant profiling was carried out and estimates were made for phenolic, flavonoid and tannin content using standard methods. The total antioxidant activity of E. hirta was found highest (90.672±0.417 µg/ml) followed by E. hirta (74.641±0.171 µg/ml) and the lowest was recorded for E. milli (74.594±0.137 µg/ml). The phenolics were found in the order E. pulcherrima > E. hirta. The reducing power when analyzed by FRAP revealed highest efficiency in E. milli (157.161±0.195 µg/ml) and lowest in E. hirta (66.540±0.756 µg/ml). When observed for antimicrobial and antioxidant biological properties, all the three plants under evaluation depicted almost similar range of activity.
Key words : : Antimicrobial activity, antioxidant profiling, Euphorbia hirta, Euphorbia milli and Euphorbia pulcherrima