RAJKUMARI SUPRIYA DEVI, B. L. MANJULA, SUCHETANA MUKHERJEE, DEVILAL N. WATAKHERE, KUNJA BIHARI SATAPATHY AND SANJEET KUMAR*
Ambika Prasad Research Foundation, Cuttack-753 014 (Odisha), India
*(e-mail: sanjeetaprf@gmail.com; Mobile: 99370 45614)
(Received: June 1, 2023; Accepted: July 1, 2023)
ABSTRACT
Validation and evaluation of food and medicinal potential, including toxicity and cytotoxicity level analysis, is an important task in a contemporary situation where the whole world is facing antimicrobial resistance and lethal diseases like cancer, corona, etc. Considering this, an effort was undertaken to evaluate the degree of cytotoxicity of specific food and medicinal plants, including Blumea flava, Ludwigia adscendens, Oenanthe javanica, Phragmites karka and Polygonum barbatum, consumed by the native population of Loktak Lake, Manipur, India. Tests on Brine shrimp (Artemia salina) lethality and plant collection were done in accordance with ethnobotanical data. The results showed that O. javanica had the highest level of cytotoxic capability against Brine Shrimp nauplii followed by L. adscendens, P. karka, B. flava and P. barbatum. The findings showed that the plant parts could be employed as anticancer medicines and should be used in low quantities. The present study offers fundamental concept for potential medication formulations.
Key words : Anticancer, Artemia salina, Loktak Lake, safe use, toxicity