Search for content, post, videos

In silico Genome-Wide Analysis of the ATP-Binding Cassette Transporter Gene Family in Pediococcus acidilactici NCDC 252 : A Strain of Dairy Origin

Department of Biochemistry, Kurukshetra University, Kurukshetra-136 119 (Haryana), India
*(e-mail :; Mobile : 9416069913)
(Received : September 18, 2019; Accepted : November 20, 2019)


ATP-binding cassette transporters are integral membrane proteins that actively transport molecules across cell membranes. NCDC 252 genome possessed genes for ABC transporter consisting of ATP binding, substrate binding and permease proteins. ABC transporter plays an important role in bacterial adaptation to its ecological niche by regulation of transport of molecules between the cell and external medium. The strain possessed genes for amino acid (including branched chain amino acids), oligopeptide, biotin, energycoupling factor and teichoic acid transporters essentially required for proteins synthesis, nutrition and its growth, respectively. Genes for osmoprotectant transport system regulate its adaptation under high osmotic conditions. Presence of these genes suggested that NCDC 252 was industrially important strain.
Key words : ABC transporters, Pediococcus acidilactici NCDC 252, in silico genome analysis, KEGG pathways