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Serological, Clinical, Hematological and Biochemical Study of Canine Infectious Hepatitis in Adult Dogs in Basrah Province, Iraq

Department of Internal and Preventive Medicine, College of Veterinary Medicine, Basrah University, Iraq
*(e-mail:; Mobile: 00964 77075 17175)
(Received : December 23, 2022; Accepted : January 29, 2023)


The current study was conducted on 84 dogs (64 unvaccinated dogs of both sexes of different breeds showing the clinical signs of canine infectious hepatitis and 20 clinically heathy dogs). The study was conducted during September 2020 to April 2021 in Basrah province, Iraq. 36/64 (56.25%) adult dogs (males and females) were positive for antibodies against CAV 1. In which male 25/38 (65.78%) were higher than female 11/26 (42.3%). There was significant increase in body temperature, respiratory and heart rates, when compared with control group. Contrarily, there was decrease in the TRBCs, Hb, PCV and MCHC with increase in the MCV. Even clotting, prothrombin and activated thromboplastine time was affected. The biochemical analysis indicated significant increase in AST, ALT, ALP, GGT and total bilirubin. However, significant decrease was encountered in total protein values. Further, kidney functions showed increase in BUN, creatinine level and BUN/creatinine ratio in diseased adult dogs.
Key words : Canine adenovirus, CAV 1, CAV 2, infectious canine hepatitis