POOJA DADHWAL, HARISH KUMAR DHINGRA* AND VINAY DWIVEDI
Department of Biosciences, School of Liberal Arts and Sciences, Mody University of Science and Technology,
Lakshmangarh-332 311 (Rajasthan), India
*(e-mail:harishdhingra2000@gmail.com; Mobile: 94615 36233)
(Received: January 20, 2023; Accepted: February 25, 2023)
ABSTRACT
Metallic-element like gold, copper and silver NPs has numerous applications in the field of bio-technology
and bio-medicine. Copper nanoparticles (CuNPs) have exhibited significant properties like anti-microbial and anti-oxidant properties. The aim of this research was to synthesize copper nanoparticles by using Hippophae rhamnoides L. stem and to evaluate their anti-microbial properties. The anti-microbial activities of H. rhamnoides L. stem-CuNPs were analyzed by using growth zone inhibition methods against Staphylococcus aureus and Escherichia coli bacteria strains and P. chrysogenum and C. albicans fungal strains. The results indicated that plant-CuNPs had the maximum antifungal activity against P. chrysogenum with 12 mm zone of inhibition and antibacterial activity against S. aureus (11 mm) at 80 µl of concentration. These outcomes showed that such copper NPs made with H. rhamnoides L. stem extracts had significant anti-bacterial properties and could be used as possible medications to prevent diseases.
Key words : Copper nanoparticles (CuNPs), Hippophae rhamnoides L., sea buckthorn, antimicrobial