MUHAMMAD LUTHFI*, PRIYAWAN RACHMADI, AQSA SJUHADA OKI AND AGUNG SOSIAWAN
Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
*(e-mail : m.luthfi@fkg.unair.ac.id; Phone : +6281357898957)
ABSTRACT
In children younger than three years are considered as Severe Early Childhood Caries (S-ECC). This analytic observational study compared the level of CD8+ expression in saliva of children with S-ECC and free-caries children. Lymphocyte cells contained in saliva acquired by instructing the experimental subjects to gargle 10 ml of 1.5% NaCl solution. The expression of T lymphocyte (CD8+) was analyzed by means of flow cytometry. The expression of T lymphocyte (CD8+) in children with S-ECC (0.3400±0.14726) was higher than free-caries group (0.3250±0.11301) with P value of 0.655.
Key words : T lymphocyte (CD8+), S-ECC, adaptive immunity